This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

This seems to be the case for apoptotic neutrophils and fibroblasts, but not for apoptotic lymphocytes. It seems, however, that in all cases CD47 becomes qualitatively changed on apoptotic cell ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.