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Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain. (IMAGE)
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Impact of CD2AP deficiency in microglia in Alzheimer’s disease (IMAGE)
Microglial CD2AP levels are increased in AD, leading to elevated CSF1R signaling and C1q expression and cytoskeleton remodeling in microglia, resulting in the formation of disease-associated ...