A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these cells enable ...

Thanks to its head (a CD40 dendritic cell engager) and tail (a commutable antigen from virus or tumor), each AMV induces a specific, controlled and broad immune response. The ANRS VRI06 trial was ...

6 glucan showed that these β-glucans increased the activation of the dendritic cells and upregulated the important surface ...

A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), in collaboration with the Instituto ...

CD40 agonists have had mixed results in cancer ... The rationale behind the drugs is that stimulating CVD40, a receptor on dendritic cells of the immune system, enhances their ability to display ...

These include antibodies directed at FLT3, AXL and CD40 with the purpose of mobilizing and activating dendritic cells. “Despite being a key cell type for mounting an antitumor immune response ...

We here evaluated the effects of LBH589 on human myeloid dendritic cells (DCs ... (human leukocyte antigen-ABC↓) and T-cell co-stimulation (CD40↓ and CD86↑). LBH589 decreased both protein ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found on ...

MyD88 from white blood cells called monocytes, and CD40 from dendritic and other cells. The TCR and antibody components served as an "invader detecting device," recognizing cancer cells as foreign ...

Results from a Phase I clinical trial of a dendritic cell targeting prophylactic HIV vaccine published in the Journal eClinical Medicine Thursday, March 13, 2025 Today's Paper ...