But when U.S. National Institute of Standards and Technology researchers Christina Bergonzo and Alexander Grishaev put ...

the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a 20-DNA-letter long sequence that matches part of the guide RNA sequence.

"By visualizing how these complex structures assemble and function, we're opening doors to entirely new approaches in ...

The genetic code acts as life’s instruction manual, telling cells how to build proteins from DNA and RNA. Though it's a ...

First, short DNA sequence tags called unique molecular identifiers (UMIs) are added to cells. They attach to DNA and RNA molecules and begin making copies of themselves. This starts a chemical ...

This pathway, or others like it, could explain why some inheritable traits between generations can’t be explained exclusively via DNA and RNA. "There are a lot of traits and disorders that we ...

First, a DNA sequence is designed in a computer-assisted process. It codes for the shape that the RNA should assume after folding. To approximate the desired structure, suitable RNA motifs must be ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...

With Non-Invasive Prenatal Testing (NIPT), molecular genetics enables the correlation between changes in the structure and ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

But to date this technology -- which allows scientists to use a 'guide' RNA to modify DNA sequences and evaluate the effects -- is able to target, delete, replace, or modify only single gene ...