Eosinophilic esophagitis (EoE) is a chronic esophageal inflammatory disease of undetermined pathophysiology that results in dense mucosal eosinophilia and esophageal dysfunction. In childhood ...

First described nearly 20 years ago, eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus characterized by eosinophilic infiltration of the esophageal epithelium. Over 50% of ...

While there is no cure, treatments like dietary changes, medications, and medical procedures can reduce inflammation and ...

Eosinophilic asthma is a severe form of asthma caused by excess amounts of white blood cells that cause inflammation in the respiratory system. It’s rare and difficult to treat, and requires ...

Eosinophils are pro-inflammatory white blood cells thought to protect against parasitic infections, but in excessive numbers they can cause tissue and organ damage, as observed in eosinophilic ...

This causes a buildup of a type of white blood cell called eosinophils in the esophagus, leading to inflammation. The inflammation causes the esophagus to become narrow, making it hard to swallow.

Following recent approvals in the EU, China and the U.S., this approval was based on pivotal Phase 3 results in adults with elevated eosinophils ...

First approved in 2015 for severe asthma with an eosinophilic phenotype in the US, mepolizumab is a monoclonal antibody that targets and binds to interleukin-5 (IL-5), a key messenger protein ...

A Prescription Drug User Fee Act target date of December 16, 2025 has been assigned to the application. The Food and Drug Administration (FDA) has accepted for review the Biologics License ...

Eosinophilic esophagitis (EoE) is a chronic esophageal inflammatory disease of undetermined pathophysiology that results in dense mucosal eosinophilia and esophageal dysfunction. In childhood ...