Coagulation of blood involves proteins called clotting factors. A total of 13 clotting factors - designated by Roman numerals I to XIII - are found in the blood. Injury to blood vessel triggers ...

The indications, pharmacokinetics, and therapeutic guidelines for available coagulation products are reviewed. Patients with hemophilia, von Wille-brand's disease (VWD), or acquired inhibitors to ...

(3 to 9 units) of fresh-frozen plasma were infused ... The levels of each of the clotting factors after the plasma transfusions were variable. The increase in clotting factor activities in each ...