Huntington's disease is an autosomal dominant genetic disorder caused by extended cytosine-adenine-guanine (CAG) trinucleotide repeats in the huntingtin gene.

Before receiving a kidney transplant, patients with autosomal dominant polycystic kidney disease often undergo a nephrectomy. But there hasn’t been clear guidance on who’s a good candidate ...

Approximately 160,000 individuals in the United States are diagnosed with polycystic kidney disease, and the global prevalence of the condition is estimated at between 4 million and 7 million people.

People with autosomal dominant polycystic kidney disease (ADPKD) are at a high risk of developing kidney failure during their lives. Although there are many strategies that can be used to help ...

HD is one of the most common autosomal dominant ... we developed the first human genomic transgenic mouse model of Huntington’s disease with long—about 120—uninterrupted CAG repeats ...

Among patients with autosomal dominant polycystic kidney disease, outcomes were strongly associated with race and ethnicity.Further, investigators found Black and Hispanic patients with autosomal ...

Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology , 2022; ASN.2022010053 ...

The new findings published in the article titled, “Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease,” overturn the ...

Patients with autosomal dominant polycystic kidney disease have a preferable cardiac profile before transplantation and better survival and major adverse cardiovascular event-free survival rates ...