Note that while they may serve as sensory receptor cell specializations, primary cilia can simultaneously support major IFT functions of the cell (Figure 3). The primary cilium has gone from being ...

Based on published work, I hypothesize that the C. elegans TUBBY family member, TUB-1, requires a motor protein adapter called the IFT-A complex to help TUB-1 shuttle ciliary cargo into the cilia. To ...

now reveal an unexpected role for the intraflagellar transport (IFT) mechanism — a process that mediates ciliary assembly in most eukaryotic cells — in haematopoietic cells (which lack cilia ...

a protein component of the intraflagellar transport (IFT) complex B. This results in dysfunctional cilia, which explains certain symptoms that are specific to COVID-19. However, the precise ...