It's a challenging diagnosis, as the disease mimics other conditions.A majority of the time, if the cell accumulation turns into a mass, a doctor will do a biopsy to make sure it's not cancer. As ...

An elderly man with immunoglobulin G4-related disease (IgG4-RD) with kidney involvement and monoclonal gammopathy was successfully treated with corticosteroid therapy. This case report was published ...

However, a nationwide Japanese survey reported the rates of these findings in bile duct biopsy samples as only 32.9%, 16.9%, 0.6%, and 0.0%, respectively. 4 “This low sensitivity is attributed ...

IgG4-related disease is an autoimmune disorder affecting millions and has no established cure. Previous research indicates that T cells, a major component of the immune system, and the ...

In patients with IgG4-related disease, the serum IgG4 concentration is typically high and often very, very high. Example, elevated up to five or 10 times the upper limit of normal is not unusual ...

The monoclonal antibody Uplizna met key endpoints in a phase 3 trial for the treatment of IgG4-related disease, marking the first time a placebo-controlled study has shown benefit in the condition ...

At baseline, 62 (45.9%) participants had newly diagnosed IgG4-RD and 73 (54.1%) had recurrent disease. Both groups received identical glucocorticoid tapers. Overall, 127 (94.1%) completed the 52 ...

Meeting Coverage > ACR NMO Drug Looks Good for IgG4-Related Disease — Phase III results, now published, should support approval. by John Gever, Contributing Writer, MedPage Today November 15, 2024 ...