In a new study, a team led by medical researchers at The Ohio State University has determined that these vesicles contain an ion channel—a protein that opens a corridor allowing electrical ...

Although several types of excitable cells exist — including neurons, muscle cells, and touch receptor cells — all of them use ion channel receptors to convert chemical or mechanical messages ...

Today it seems self-evident that neurons make their electrical signals by opening gates of water-filled pores (ion channels) in the plasma membrane. But it was not always so. Remarkably ...

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function ...

Xenon's lead asset, azetukalner, shows promise in treating focal onset seizures with positive phase IIb results and upcoming ...

View Full Profile. Learn about our Editorial Policies. The elusiveness of single ion channels intrigued researchers for another quarter of a century. In his youth, Erwin Neher, now a biophysicist at ...

This important computational study investigates homeostatic plasticity mechanisms that neurons may employ to achieve and maintain stable target activity patterns. The work extends previous analyses of ...

Our laboratory uses a combination of structural biology and biophysical techniques to discover how ion channels and membrane-embedded enzymes function at the atomic level. The proteins we study are ...

Maxion Therapeutics Ltd. has raised $72 million (£58 million) in a series A financing to support its development of antibody-based Knotbody drugs for ion channel- and G protein-coupled receptor (GPCR) ...

In plants, guard cells control the stomatal opening by expanding and contracting through ion flux. When a plant senses light, a signal is sent to the guard cell to increase its ion content, which ...