Game status: Isaac Guerendo is ACTIVE for Week 15 against the Rams. The San Francisco 49ers host the Los Angeles Rams in a Week 15 Thursday Night Football game that is a must-win for both teams.

The Minnesota Vikings traded for running back Jordan Mason on Saturday, adding depth to their backfield for the 2025 season.

Entering a do-or-die matchup vs. the Chicago Bears this Sunday, the San Francisco 49ers are banking on rookie running Isaac Guerendo to fill the shoes left by reigning Offensive Player of the Year ...

The San Francisco 49ers traded away running back Jordan Mason to the Minnesota Vikings on Saturday night. The 49ers sent ...

Louisville Cardinals running back Isaac Guerendo runs an official 4.33-second 40-yard dash at the 2024 NFL Scouting Combine. Watch the full on-field workout from Oklahoma Sooners safety Billy ...

San Francisco 49ers running back Isaac Guerendo's second touchdown of day gets 49ers to 30-point mark vs. Chicago Bears. Watch the highlights from Super Bowl LIX between the Kansas City Chiefs and ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class ...

New Minnesota Vikings running back Jordan Mason shared a very telling reaction following his trade from the San Francisco ...

The star running back racked up 1711 yards on the ground and 24 total touchdowns on the way to leading Arizona State to the ...

The San Francisco 49ers backfield got a little thinner with Jordan Mason headed to the Minnesota Vikings in a trade.

They just traded Jordan Mason who was their leading rusher last year. Now they have Isaac Guerendo who carried the ball 84 times last season, and Christian McCaffrey who carried it 50 times.