Isaac Guerendo, who spent five years with the Badgers before playing last year at Louisville, was taken in the NFL draft's fourth round by the 49ers.

There's still some work to do for the San Francisco 49ers in their backfield after trading Jordan Mason to the Minnesota Vikings.

The San Francisco 49ers' regular season was defined by frustration and disappointment and so far, Kyle Shanahan and Co. have ...

The San Francisco 49ers traded away running back Jordan Mason to the Minnesota Vikings on Saturday night. The 49ers sent ...

The Minnesota Vikings traded for running back Jordan Mason on Saturday, adding depth to their backfield for the 2025 season.

Louisville Cardinals running back Isaac Guerendo runs an official 4.33-second 40-yard dash at the 2024 NFL Scouting Combine. Watch the full on-field workout from Oklahoma Sooners safety Billy ...

San Francisco 49ers running back Isaac Guerendo's second touchdown of day gets 49ers to 30-point mark vs. Chicago Bears. Watch the highlights from Super Bowl LIX between the Kansas City Chiefs and ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class ...

New Minnesota Vikings running back Jordan Mason shared a very telling reaction following his trade from the San Francisco ...

The star running back racked up 1711 yards on the ground and 24 total touchdowns on the way to leading Arizona State to the ...

The San Francisco 49ers backfield got a little thinner with Jordan Mason headed to the Minnesota Vikings in a trade.

Chez Mellusi (21 carries, 98 yards), Allen (18-92) and Isaac Guerendo (9-42) combined to rush for 232 yards. Mertz passed for ...