The seventh-seeded Denver Broncos make their first postseason appearance since winning Super Bowl 50 when they take on the second-seeded Buffalo Bills on Sunday. Buffalo is making its sixth consecutive playoff appearance,

The Buffalo Bills enter the playoffs as one of the best teams in the NFL. An explosive offense, a strong defense, and a possible MVP in Josh Allen. If they're not the AFC's favorite to make the Super Bowl,

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Over the weekend the Buffalo Bills suffered their fourth loss of the season in a 23-16 loss to the New England Patriots. The loss didn't have much of an impact

While the Broncos and their fans are likely thrilled to return to the playoffs for the first time since 2015, this is routine for the Bills. However, advancing past the Wild Card round has often been a hurdle for Buffalo. This game marks the starting point of the Bills’ journey to return to the Super Bowl.

SportsLine AI evaluated the 2025 NFL Wild Card Weekend odds and revealed its NFL picks, NFL score predictions and NFL best bets for every game

Pregame analysis and predictions of the Denver Broncos vs. Buffalo Bills NFL game to be played on January 12, 2025 on ESPN.

See who's in and who's out for the Wild Card Round matchup between the Buffalo Bills and Denver Broncos on January 12, 2025.