As a result, CLEC1A was identified as a candidate receptor for antithrombin. Antithrombin stimulates CLEC1A on human neutrophil cells to change the morphology of neutrophils to a spherical shape ...

Shenfu Decoction can improve the chemotactic function of neutrophils, possibly through the downregulation of P2X1 receptor expression. Its effects are positively correlated with the dosage.

“This structural program relies on TGFβ signaling; disabling the TGFβ receptor in neutrophils impaired ring formation around wounds and facilitated bacterial invasion,” the scientists wrot ...

Assistant Professor Andrew Monteith's lab in the Department of Microbiology is documenting how key immune cells detect infection and how that fails to happen in people with lupus. Research ...