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To assess whether synergistic toxicity between ribavirin and nucleoside analogues was responsible for the significant weight loss we observed, we analyzed 47 patients coinfected with HIV and HCV ...
Chronic hepatitis B treatment relies on nucleoside or nucleotide analogue drugs that suppress hepatitis B virus (HBV) ...
Two new studies examine the use of the nucleoside polymerase inhibitor, R1626, to the standard therapy for hepatitis C. The reports appear in the August issue of Hepatology, a journal published by ...
Lamivudine 150mg, zidovudine 300mg; scored tabs. Lamivudine is a synthetic nucleoside analogue. Intracellularly, lamivudine is phosphorylated to its active 5′-triphosphate metabolite, lamivudine ...
Acquisition will give BMS clinical pipeline of nucleotide/nucleoside analogs. Bristol-Myers Squibb (BMS) is buying anti-infectives firm Inhibitex for an aggregate of about $2.5 billion in cash ...
Speaking of which, the company is in preparations of beginning a phase 2b study using Imdusiran + short-course of PEG-IFNa-2a + Nucleoside Analogue to target these HBsAg-negative cHBV patients.
Now, using the new process, scientists can create new nucleoside analogues months earlier than with the previous method, paving the way for quicker drug discoveries. A paper on this research was ...
A team of researchers has found a quicker and more efficient way to create nucleoside analogs, a type of small molecule that can be used in treatments for everything from cancer to viral diseases.
New research has revealed the differences in mechanism behind cancer’s resistance to the major class of anti-cancer drugs known as nucleoside analogues. Nucleosides are molecules containing the ...