We have previously shown that pleiotropically resistant Ehrlich ascites tumour cells, which are of epithelial origin, have a significantly increased plasma membrane traffic (endo/exocytosis ...

The lyrics above, with apologies to Irving Berlin, describe protein-protein interactions on the cell membrane, most of which occur between “cheek to cheek” protein neighbors, or ...

To kill their targets, CTLs release perforin, a pore-forming toxin, which creates lesions in the target cell’s plasma membrane. Cytotoxic granzymes pass through these portals and induce target ...