The brain really is an incredible organ, and neurons are the vital link between, well, everything. The brain is anything but set in stone; how we think, feel, reason, and understand the world changes ...

This enzyme degrades monoamine neurotransmitters after their reabsorption into the presynaptic neuron. Drugs called monoamine oxidase inhibitors (MAOIs), inhibit this enzyme, resulting in an ...

A stash of neurotransmitter-packed vesicles hunkers close to the presynaptic membrane so the vesicles can fuse ... and scientists long assumed these proteins were essential to neuron signaling. For ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.

This means that the presynaptic neuron releases the neurotransmitter glutamate, which crosses the synaptic gap to bind to receptors — usually ionotropic glutamate receptors (iGluRs ...

Serafini and colleagues provide evidence that neuroligin acts as a trans-neuronal signal to induce presynaptic differentiation at neuron–neuron connections in vitro. To form a synaptic ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another.

Methylphenidate is thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. Swallow whole.

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...