Two-year recurrence rates in 618 joints successfully treated with collagenase injections indicate a recurrence rate of 19.3% for Dupuytren's disease of the hand.

The usual initial clinical presentation of Dupuytren's contracture is nodular thickening in the palm, advancing to contractures of the metacarpophalangeal and proximal interphalangeal joints. The ...

A shows contracture of left little finger after trauma, B bowing of grafted tendon, ... In the left ring finger flexion at the proximal joint was possible 40° actively and 90° passively.

Joint contractures due to prenatal or postnatal failure of supporting joint musculature, especially at the proximal hip joints Sleep difficulties such as hypoventilation Type-specific symptoms ...

Glucocorticoids are the mainstay of therapy for this disorder; these are started in moderate to high doses (e.g., prednisone 20–100 mg/d).1, 3 Resolution of eosinophilia is rapid, but softening of ...

Endo logo (PRNewsfoto/Endo, Inc.) Dupuytren contracture is a progressive hand condition in which a collagen rope-like cord forms beneath the skin of the palm, pulling fingers inward toward the ...

Camptodactyly (MIM 114200) is a digit deformity characterised by permanent flexion contracture of fifth fingers at the proximal interphalangeal (PIP) joints. The sporadic cases are common but a ...

Co announces the positive final results of an early Phase III study of its lead development product AA4500 in the treatment of dupuytren's contracture. Co says the study was comprised of a ...

The severity of the syndrome is variable. In severe cases, there may be no hip joint and the femur may be very short. In addition, proximal focal femoral deficiency (PFFD) may be associated with other ...