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Small molecule inhibitors restore normal BRAF structure, offering insight into cancer-causing mutations
Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural ...
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Structure Therapeutics Announces Selection of Lead Oral Small Molecule Amylin Receptor Agonist ACCG-2671 for the Treatment of Obesity
SAN FRANCISCO, Dec. 17, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for ...
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Scratching an Itch in Mice with New Small Molecule Inhibitors (2 of 6)
image: Sensory nerves innervating the skin are grouped together in a structure next to the spinal ... the nerves involved in detecting itch are labeled green, while nerves involved in sensing ...
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Structure Therapeutics Announces First Patients Dosed in Phase 2b ACCESS Clinical Study Evaluating Oral Small Molecule GLP-1 Receptor Agonist, GSBR-1290, for Obesity
SAN FRANCISCO, Nov. 13, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for ...
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Real-Time Imaging of Innate Immune Activity Made Possible by Radio-Labeled Molecule
Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic ...
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Insilico Medicine successfully discovered potent, selective, and orally bioavailable small-molecule inhibitor of CDK8 using generative AI
and orally bioavailable small molecule inhibitor of CDK8 for the treatment of cancer using a structure-based generative chemistry approach enabled by the Chemistry42 multi-modal generative ...