There is now convincing evidence that regulatory CD4 + T cells are essential in the control of immune responses by inhibiting the function of T helper type 1 (T H 1) and T H 2 effector cells ...

Current research suggests that T helper-type 1 cells, previously thought to mediate autoimmunity, may actual inhibit the development of experimental immune encephalomyelitis, a mouse model of ...

The study included 12 patients who suffer from a subset of Type 1 diabetes known as hypoglycemic unawareness, characterized ...

IL-4-producing B cells regulate T helper cell dichotomy in type 1- and type 2-controlled diseases Journal: Proceedings of the National Academy of Sciences of the United States of America Published: ...

Immune checkpoint inhibitors have changed the future of cancer care. These powerful treatments use the body’s own immune ...

Scientists have discovered why the flu vaccine can perform poorly. They found that a specific type of immune cell, called T follicular helper cells, indirectly controls the anti-influenza response ...

In the years that followed, other groups identified more types of innate lymphoid cells and noticed a peculiar pattern: For every class of T cell, an ILC counterpart exists that resembles it. 6 For ...

Q I have Type 1 diabetes. I try to stay healthy and keep my blood sugar under control, but it feels like a fight every day. I ...

Of course, people with type 1 diabetes had it worse. Their tissue samples showed the T cells very close to - and even infiltrating - the islets. We can't say that these are the only culprits in ...

A new study sheds light on how a rare type of helper T cell, called Th9, can drive allergic disease, suggesting new precision medicine approaches to treating allergies in patients with high levels ...

Sana’s product for Type 1 diabetes, SC451, aims to replace a patient’s lost islet cells with genetically engineered ones that are derived from donors or grown from iPSCs.

The research indicates that reprogrammed T helper cells adopt characteristics of a new T helper cell type while preserving some of their original traits, making them “super powerful and potent ...