We describe here a population of TR cells that developed in vivo from naive CD4+CD25− T cells during a T helper type 1 (TH1)–polarized response, distinct from CD25+ TR cells.

Immune checkpoint inhibitors have changed the future of cancer care. These powerful treatments use the body’s own immune ...

In the years that followed, other groups identified more types of innate lymphoid cells and noticed a peculiar pattern: For every class of T cell, an ILC counterpart exists that resembles it. 6 For ...

Sana’s product for Type 1 diabetes, SC451, aims to replace a patient’s lost islet cells with genetically engineered ones that are derived from donors or grown from iPSCs.

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, ...

Scientists have discovered why the flu vaccine can perform poorly. They found that a specific type of immune cell, called T follicular helper cells, indirectly controls the anti-influenza response.

The abnormal T cells in question is called a T follicular helper 17 (T FH 17) cell—meaning it functions as a T FH cell but also displays T helper 17 (T H 17) cell signatures.

'Black sheep' of helper T cells may hold key to precision allergy treatment Date: May 3, 2023 Source: University of Pittsburgh Summary: A new study sheds light on how a rare type of helper T cell ...

The autoimmune disease, lupus – officially known as systemic lupus erythematosus (SLE) – is a challenge to treat and a burden to live with. The random flare-ups of pain, inflammation, and fatigue that ...