Having a better midlife diet associated with better functional connectivity between the hippocampus and both the occipital ...

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

In other words, every successive birth cohort has a lower risk of dementia than did its predecessor. Extrapolated forward, these rates would predict only a 25 percent bump in dementia cases by 2050.

Trust Your Intuition? Starting with 126,640 people who downloaded the Intuition study app, recruits went through consent, eligibility screening, study orientation, and an initial CANTAB assessment, ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

For years, the Alzheimer’s disease field has been on a quest for the perfect blood marker. Such a test could spare patients from invasive lumbar punctures, broaden care access, and allow AD cases to ...

Not the Same. In amyloid-negative people (left) few tangles accumulate over a decade. In amyloid-positives (right), tangles grow faster in women (red) than men (blue). [Courtesy of Gillian Coughlan, ...

Screening large genetic datasets can uncover harbingers of neurodegenerative disorders such as Alzheimer’s disease. For AD, most older genome-wide association studies have relied heavily on ...