This explainer outlines how neurons and glial cells coordinate electrical and chemical signals to form complex brain networks that govern thought, behavior, and consciousness. It also explores how ...

Neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS (amyotrophic lateral sclerosis) are debilitating conditions ...

In many neurodegenerative diseases, one common symptom is the formation and accumulation of insoluble, membrane-less protein condensates ... of ATP needed for all energy processes in the cell is only ...

The blood-brain barrier border protects the brain by regulating the flow of molecules, peptides, and cells, but it also keeps ...

In many neurodegenerative diseases, one common symptom is the formation and accumulation of insoluble, membrane-less protein ...

Neurodegenerative disease like Alzheimer's, Parkinson's, and ALS (amyotrophic lateral sclerosis) are debilitating conditions that affect millions of ...

We are investigating the mechanisms by which cancer mutations deregulate the normal processes of cellular function and growth ...

WHEN an impulse invades the soma and dendrites of a mammalian motoneurone, the spike potential is always followed by a phase of increased membrane potential ... the Renshaw cell mechanism 2.

As a result, they find that Cdh13, a membrane-anchored cadherin , is downstream of Bcl11b and mediates its cell-autonomous role on axon outgrowth. To validate the role of Cdh13 as a mediator of Bcl11b ...

The advantages to cell-derived membrane vesicles are multiple ... and pClamp10.5 software (Axon Instruments, Inc) for controlling membrane voltage and data acquisition. The recorded signal was ...