Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

For example, DELTEX E3 ligases were reported to ubiquitylate a hydroxyl group on free NAD + and ADP-ribose in vitro, generating a noncanonical ubiquitin ester-linked species. In this report, we show, ...

Spectroscopy is a key tool for identifying chemical compounds and analyzing molecular structures. Learn how to read and ...

DENV was labeled with Alexa Fluor 594 succinimidyl ester (AF594SE, Molecular Probes, Invitrogen) according to a previous study (Zhang et al., 2010). The labeled viruses were purified using Amicon ...

Cells were fixed and surface stained with fluorochrome-conjugated antibodies specific for human CD3 ... Carboxyfluorescein succinimidyl ester-labelled CD8+ T cells were adoptively transferred by ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

The Bible’s Queen Esther was one of the defining Dutch divas of the 17th century and muse to some of Amsterdam’s greatest painters — among them Rembrandt Harmenszoon van Rijn. “The Book of Esther in ...

The authors' demonstration that impaired olfactory perception reduces caterpillar performance and increases susceptibility to parasitism is solid. These findings highlight the ecological significance ...

Stark Library is celebrating Black history, and particularly that of Esther Archer. "Each year here at Stark Library we plan programs, curate displays, organize book lists, and encourage our ...

In the dipstick method, neutrophilic esterases catalyze the hydrolysis of esters to produce their respective alcohols and acids. The alcohols produced then react with a diazonium salt to produce a ...