amides, lactams, and biaryls. Consequently, different types of skeletal modification transformations have been developed. The major topics covered include the following: (1) Skeletal rearrangement and ...

This approach allows amides to serve as transient directing or protecting groups ... This powerful skeletal modification unlocks new pathways for constructing cyclic frameworks with minimal synthetic ...

Peptides designed by artificial intelligence restrict both drug-resistant bacteria and rapidly evolving viruses.

England U20s have been hugely successful in the past few years, having won the Six Nations and the U20 Championship last year, while looking close to a Grand Slam this year. Following three wins from ...

Peptide-drug conjugates (PDCs) represent an emerging class of targeted therapeutic agents that consist of small molecular drugs coupled to multifunctional peptides through cleavable or non-cleavable ...

This revision of important work is a versatile addition to the chemical protein modifications and bioconjugation toolbox in synthetic biology. The technology developed cleverly uses Connectase to ...