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Eosinophilic gastroenteritis (EGE) is characterized by dense eosinophilic inflammation of one or several digestive tract sections. The symptoms include abdominal pain, weight loss, vomiting and ...
First described nearly 20 years ago, eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus characterized by eosinophilic infiltration of the esophageal epithelium. Over 50% of ...
METREX involved patients with a range of eosinophil levels and showed a statistically significant improvement for Nucala versus placebo on exacerbation rates. However, in METREO – which focused ...
Drilling down into the data, however, there was a 37% reduction in exacerbations in a subgroup of patients with a baseline eosinophil count (BEC) 150 cells/μL or more, a population that Amgen and ...
Objectives Eosinophils possess pro-inflammatory functions in asthma. However, our recent studies have suggested that innate lymphoid cells type 2 (ILC2s) and eosinophils have proresolving properties ...
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