Achalasia, a chronic oesophageal motility disorder, is defined by impaired lower oesophageal sphincter relaxation and absent peristalsis, leading to symptoms such as dysphagia and regurgitation.

a drug candidate that is trying to be the first approved therapy in the US for eosinophilic oesophagitis (EoE). Takeda said it had received a complete response letter from the US regulator that is ...

The company has secured $100 million upfront – with the remaining $160 million due if the erosive oesophagitis approval comes through – from Sagard Healthcare Partners, NovaQuest Capital ...

The first PPI to reach the market was omeprazole, which is indicated for the treatment of duodenal and gastric ulcers, gastro-oesophageal reflux disease, erosive oesophagitis, hypersecretory ...

Oesophagitis This is the inflammation of the oesophagus which usually happens due to gastroesophageal reflux disease (GERD). There are times when one might have abnormal blood vessels, small ...

However, there is a serious lack of agreement about how to describe and classify the appearance of reflux oesophagitis AIMS To examine the reliability of criteria that describe the circumferential ...

Objective Disruption of the epithelial barrier plays an essential role in developing eosinophilic oesophagitis (EoE), a disease defined by type 2 helper T cell (Th2)-mediated food-associated and ...

Many experts maintain that GERD is caused by dysfunction of the gastroesophageal barrier and that gastric acid secretion is not the primary underlying defect. 2 A few studies have, however, raised ...

H. pylori test and treat in case of unexplained iron deficiency anemia n.m. n.m. H. pylori test and treat in case of idiopathic thrombocytopenic purpura n.m. n.m. MALToma: Mucosa-associated ...