Systemic therapy represents the standard of care treatment for patients with advanced hepatocellular carcinoma (HCC). Given ...

Background IBD is a chronic inflammatory condition driven by complex genetic and immune interactions, yet preclinical models ...

Correspondence to Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; ...

Introduction Hepatitis C (HCV) is a blood borne virus that is curative in over 90% of cases. The NHS England HCV Elimination Programme is working to eliminate HCV in advance of the WHO goal of 2030, ...

Background Inflammatory bowel diseases (IBDs) are characterised by dysbiosis and a leaky gut. The NADPH oxidase dual oxidase 2 (DUOX2) is upregulated in patients with IBD, yet its role in driving the ...

Objective Both the gut microbiome and host genetics are known to play significant roles in the pathogenesis of IBD. However, the interaction between these two factors and its implications in the ...

2 Department of Pathology, School of Forensic Medicine, Shanxi Medical University, Taiyuan, China 3 Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science ...

Objectives National guidelines for the management of irritable bowel syndrome (IBS) recommend that psychological therapies should be considered, but their relative efficacy is unknown, because there ...

Novel Bacteria and Drug Discovery Research Group (NBDD), Microbiome and Bioresource Research Strength (MBRS), Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Malaysia ...

Mr C P Barham, University Department of Surgery, Bristol Royal Infirmary, Bristol BS2 8HW, UK. Background—Diffuse oesophageal spasm (DOS) is a potential cause of intermittent chest pain and/or ...

Introduction Post endoscopy upper gastrointestinal cancer (PEUGIC) is proposed as a key performance indicator by the British Society of Gastroenterology. We have examined the incidence of PEUGIC ...