Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the ...

Phase 2 ARCHER Data Support Therapeutic Potential for ANX007 to Preserve Vision in Patients who have Dry Age-related Macular Degeneration (AMD) with Geographic Atrophy (GA) Phase 3 ARCHER II Trial ...

Cheyney, PA, May, 5 2025 - Navrogen, Inc., a biopharmaceutical company specialized in developing antibody-based therapies for ...

C1q is also vital in monoclonal antibody (mAb) therapy, as it attaches to the Fc region of antibodies, initiating complement-dependent cytotoxicity (CDC). Here, we generated a humanized C1Q model ...

The purified antibody was characterized for conjugation specificity and efficiency and used in a functional antigen-binding assay. To quantify the amount of biotinylation on the rat anti-HRP ...

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She was evaluated by allergy/immunology for chronic, recurrent urticaria and found to have low C3 (74 mg/dL), C4 (8 mg/dL) and CH50 (35 U/mL) with high C1q-binding antibodies (>100). The patient ...

The prevalence of allergic, neurodevelopmental, and autoimmune conditions was similar between children born to anti-Ro antibody-positive mothers vs the general population. Children born to anti-Ro ...

The heatmap represents the relative intensity of antibody binding to RBDs and blocking of the RBD-ACE2 interaction. Blue (0–25%), green (25–50), orange (50–75%) and red (>75%). NTD binding was ...

The beauty of this company is that its inhibition of C1q can be applied towards other ... file its BLA of this intravenous [IV] monoclonal antibody for the treatment of this patient population ...

Mice with targeted SAP gene deletions spontaneously develop antinuclear autoimmunity and severe glomerulonephritis—a phenotype that resembles SLE. [53] As in mice with deficiencies of the early ...