Immunological tests can differentiate proliferative from non-proliferative lupus nephritis, but anti-C1q antibodies and urinary erythrocytes have the best predictive power to dist ...

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from ...

Phase 2 ARCHER Data Support Therapeutic Potential for ANX007 to Preserve Vision in Patients who have Dry Age-related Macular Degeneration (AMD) with Geographic Atrophy (GA) Phase 3 ARCHER II Trial ...

Immutep believes its LAG-3 candidate eftilagimod alpha may have a path to approval in first-line head and neck cancer after ...

C1q is also vital in monoclonal antibody (mAb) therapy, as it attaches to the Fc region of antibodies, initiating complement-dependent cytotoxicity (CDC). Here, we generated a humanized C1Q model ...

The purified antibody was characterized for conjugation specificity and efficiency and used in a functional antigen-binding assay. To quantify the amount of biotinylation on the rat anti-HRP ...

Harmful infectious organisms are identified as invaders due to their antigens (distinct molecules on their surface). Each antibody produced by your immune system binds to a specific antigen and then ...

The beauty of this company is that its inhibition of C1q can be applied towards other ... file its BLA of this intravenous [IV] monoclonal antibody for the treatment of this patient population ...

GLUTARALDEHYDE, a di-aldehyde fixative, has been found to bind antibodies rapidly and permanently to antigens of red blood cells. The system investigated and described in this report was similar ...

Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17/a, 43124 Parma, Italy ...

Titration curves were plotted for all antigens tested and the end-point titers were determined ... for 1 hour at room temperature, followed by an anti-C1q-PE antibody (Santa Cruz, #sc-53544 PE). For ...