Too much LRRK2 in the brain changes the structure of cells by causing them to lose their "antenna" (technically the primary cilia) that allows them to send and receive chemical messages. In a healthy ...

Cilia remove inhaled pathogens from the respiratory tract, carry cerebrospinal fluid across brain cavities, transport eggs from the ovary to the uterus, and drain mucus from the middle ear to the ...

The researchers also used immunofluorescence microscopy to visualize proteins on live beta cells. They observed that the cilia contained motor proteins that are responsible for active motion in ...

Mechanical manipulation of cilia was critical to the study “Mechanical manipulation of immotile LRO cilia activated intraciliary calcium transients that required the cation channel Polycystin-2.

Cilia, hair-like structures on cell surfaces, have been identified as a biological link between autism and congenital heart disease. Mutations in genes affecting cilia disrupt both brain and ...