AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

New research uncovers an immune pathway driving acute chest syndrome in sickle cell disease; blocking it with approved drugs ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

The FDA granted fast track designation to SAR446597, an intravitreal gene therapy for the treatment of geographic atrophy due ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

SNY's SAR446597, a one-time intravitreal gene therapy, secures FDA fast track tag for geographic atrophy due to age-related ...

Sanofi's SAR446597 earns fast track designation in the US for geographic atrophy due to age-related macular degeneration ...

Sanofi's SAR446597 earns fast track designation in the US for geographic atrophy due to age-related macular degeneration <li /> Designat ...

Functional enrichment clustering analysis revealed a significant association between DEGs and the complement and coagulation cascade pathways. The PPI network was constructed with 155 nodes and 105 ...

The hedgehog signaling pathway helps regenerate damaged tissue in the airways and pancreas. Activating it may protect tissue against smoke inhalation and prevent diabetes progression.

The Warburg effect, a hallmark of cancer, entails a metabolic shift from oxidative phosphorylation to aerobic glycolysis and is tightly regulated by complex signaling pathways. Decoding the dynamic ...