A newly discovered pathway in a plant process could help farmers grow more successful crops, particularly in places where harsh, high light stresses plants.

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

An international study led by researchers at the University of Colorado Anschutz Medical Campus has identified a promising ...

ARO-C3 is an investigational RNA interference therapeutic designed to reduce liver production of complement component 3 as a potential therapy for various complement-mediated diseases.

C3G and IC-MPGN are rare kidney conditions. They occur when a part of the immune system, called the complement system, doesn’t work as it should.

Their findings not only reshape the century-old understanding of the complement system but also open new avenues for therapies that could specifically block this harmful pathway in patients with ...

The following is a summary of “Prognostic role of activation of the complement pathways in the progression of advanced IgA nephropathy to end-stage renal disease,” published in the October 2024 issue ...

SARS-CoV-2 “steals” our proteins to protect itself from the immune system Virus hijacks three important host proteins that dampen the activity of the complement system Peer-Reviewed Publication ...

These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. Disruption of the complement system appears to precede the onset of islet autoimmunity (IA ...

Researchers have identified a blood protein ‘signature’ in the complement system, part of the immune system, of patients with long COVID that may improve the diagnosis and lead to a treatment ...

In IgAN, the abnormal IgA activate the complement system through the alternative or the mannose-binding lectin pathway. In LN, data on humans have documented abnormalities of fB.