Our data indicate that blocking the complement system exacerbates LCWE-induced KD vasculitis, potentially by impairing C3-mediated clearance of bacterial components. Our studies reveal the ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

The hazard of the progression of intermediate age-related macular degeneration (iAMD) was higher in those whose complement pathways were not regulated.

A team of scientists has uncovered how an ancient immune system, the complement system, decides when to launch an attack—revealing a hidden mathematical tipping point based on the spatial density of ...

The new pathways for the senior school are out. And students are spoilt for choice. The pathways are akin to combinations in the old A-level system. Students will need a lot of guidance from ...

C3G and IC-MPGN are rare kidney conditions. They occur when a part of the immune system, called the complement system, doesn’t work as it should.

And so I think that other pathways are going to be needed. Continuing to go down the pathway of complement inhibition, I’m not sure it’s adding much to what we currently have, and that, quite ...

Throughout the U.S., only 8 percent of hospitals along with 14 Veteran Affairs programs are recognized as Pathway to Excellence organizations by the American Nurses Credentialing Center. The Pathway ...