Thalamic neurons, particularly ventral intermediate thalamic nucleus (VIM) neurons, characteristically discharged with a burst frequency of 4-5 Hz corresponding to the tremor frequency.

DBS is a remarkable therapy that delivers electrical impulses to target areas in the brain, including the subthalamic nucleus (STN), globus pallidus internus (GPI), and ventral intermediate nucleus of ...

In a small study that followed patients for up to 10 years, investigators found the beneficial effects of DBS of the ventral intermediate thalamic nucleus (Vim) declined over time.

Targets include the ventral intermediate nucleus of the thalamus, which shows promise for relieving tremor associated with some neurodegenerative conditions.

“A significant limitation of standard MRI sequences is that the ventral intermediate nucleus, dentatorubrothalamic tract, and other deep brain nuclei cannot be clearly identified,” said the ...

The main challenge in both of these procedures, however, lies in the correct targeting of the ventral intermediate (VIM) nucleus, a pea-sized region located at the centre of the thalamus that’s ...

MRI-guided HIFU ablation of the ventral intermediate nucleus of the thalamus has been approved by the Food and Drug Administration for treatment of essential tremor and tremor-dominant Parkinson's.

With this approval, the system is now indicated to target the subthalamic nucleus, ventral intermediate nucleus, and internal globus pallidus. “The internal segment of the global pallidus, ...