A Parkinsonian mystery—how PINK1 locks onto malfunctioning mitochondria—now has a structural solution. Researchers at the University of Melbourne led by Sylvie Callegari, Alisa Glukhova, and David ...

Researchers at Johns Hopkins Medicine discovered that mitochondrial proteins Parkin, PINK1, and OMA1 act as guardians of ...

Scientists have made a potentially “life-changing” discovery that could pave the way for new drugs to treat Parkinson’s disease. Experts have known for several decades that the PINK1 protein ...

First discovered more than 20 years ago, PINK1 is a protein directly linked to Parkinson’s disease, but until now, no one has seen what human PINK1 looks like, or how PINK1 attaches to ...

Known as PINK1, the protein has been linked to the disease for decades but its structure and how to switch it back on have remained elusive – until now. When it’s functioning properly ...

But in a recent paper published in Science, researchers have had their first good gawk at the protein linked to the development of the condition (PTEN-induced putative kinase 1, or PINK1).

Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a new function of the DNA ...

First discovered over 20 years ago, PINK1 is a protein directly linked to Parkinson’s disease – the fastest growing neurodegenerative condition in the world. Until now, no one had seen what human ...

For instance, scientists have discovered that having certain genes may increase a person’s risk for developing Parkinson’s disease, such as a mutation in the PINK1 (PTEN-induced putative ...

Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...