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  1. Respiratory Syncytial Virus (RSV) - PMC - PubMed Central (PMC)

    Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract illness in young children. 1, 2, 3, 4 So effectively does RSV spread that essentially all persons have …

  2. pathogenesis of respiratory syncytial virus disease in childhood ...

    Mar 1, 2002 · The cytopathic effects of the virus explain many of the pathological findings in RSV disease. However, there is compelling evidence to suggest that the host cell immune response …

  3. The Resurgence of Human Respiratory Syncytial Virus (RSV) …

    Nov 28, 2022 · The formation of multinucleated giant cells called syncytia hallmarks a characteristic cytopathic effect of RSV; hence, viral RNA can spread without forming complete …

  4. Differential cytopathogenesis of respiratory syncytial virus

    Jan 27, 2011 · To address this hypothesis, we isolated three RSV strains from infants hospitalized with bronchiolitis and compared them with the prototypic RSV A2 in terms of cytopathology, …

  5. Advances in understanding respiratory syncytial virus infection

    Mar 1, 2013 · This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of …

  6. Multiple Respiratory Syncytial Virus (RSV ... - Journal of Virology

    Mar 14, 2022 · Our data indicated that HEp-2 and A549 cells differed systematically in their response to RSV infection with the latter cell line supporting less viral replication by mounting …

  7. Immune Responses and Disease Enhancement during Respiratory …

    RSV has a direct cytopathic effect on cells in the lung epithelium, leading to loss of specialized functions such as cillial motility and sometimes to epithelial destruction (4). In addition, a …

  8. Respiratory Syncytial Virus (RSV): Replication, Pathogenesis

    Respiratory syncytial virus (RSV), is a member of the genus Pneumovirus within the family Paramyxoviridae. RSV usually causes mild, cold-like symptoms. Most people recover in a …

  9. Respiratory Syncytial Virus and Human Bronchial Epithelium

    Respiratory syncytial virus–treated cells released significant RANTES as early as 4 hours after RSV infection of cultured human bronchial cells (P=.01). At 24 hours, the mean release of …

  10. Growth of Respiratory Syncytial Virus in Primary Epithelial Cells …

    RSV grows to moderate titers in HAE, though they are significantly lower than those in a continuous epithelial cell line, HEp-2. In HAE, RSV spreads over time to form focal collections …

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