Jul 11, 2024 · The MTA score is a visual score performed on MRI of the brain using coronal T1 weighted images in a plane parallel to the brainstem axis and through the hippocampus at the level of the anterior pons 5.

Jan 9, 2012 · A MTA-score of 2 for individuals older than 75 years of age may be normal. As the brain ages, there is an increasing deposition of iron in specific areas of the brain: mainly the basal ganglia, nucleus ruber and pars reticluaris of the substantia nigra.

Diagram depicting progressive cerebral atrophy assessed by the medial temporal lobe atrophy score.

With MRI and CT, noninvasive biomarkers for neurodegenerative diseases are widely available. This work contributes to the establishment of the easy-to-measure MTA score in the broad field of radiology and not only in neuroradiology and specialized centers.

Medial temporal lobe atrophy (MTA) is common in dementia and is also frequently seen in mild cognitive impairment (MCI). However, it can also be seen in normal aging [1, 2]. MTA has been shown to be a very strong predictor of the progression of MCI to Alzheimer’s disease (AD) [3, 4].

Oct 8, 2007 · Conclusion: Medial temporal lobe atrophy (MTA) on postmortem MRI is sensitive to primary degenerative hippocampal pathology in the very old, but not specific for Alzheimer-type pathology. MTA scores of 2 or less are not frequently associated with dementia.

Using a newly validated visual rating system, mean MTA scores of three bilateral medial temporal lobe structures were compared for subjects with no cognitive impairment (NCI) (n = 117), nonamnestic mild cognitive impairment (MCI) (n = 46), amnestic MCI (n …

Jul 13, 2004 · Visual assessment of MTA on brain MRI using a standardized rating scale is a powerful and independent predictor of conversion to dementia in relatively young MCI patients. As overlap existed in MTA scores between patients with and without dementia at follow-up, the results should be interpreted in t …

Jul 24, 2021 · Visual rating of medial temporal lobe atrophy (MTA) is often performed in conjunction with dementia workup. Most prior studies involved patients with known or probable Alzheimer’s disease (AD). This study investigated the validity and reliability of MTA in a memory clinic population.

Feb 28, 2019 · Medial temporal-lobe atrophy index (MTAi) is a new method for measuring the relative extent of atrophy in MTL in relation to the global cerebral atrophy, and is now considered to be more accurate than the MTA scale [15].