U-87 MG is a cell line with epithelial morphology that was isolated from malignant gliomas from a male patient, likely with Glioblastoma. Use these cells in your neuroscience and immuno-oncology research.

In cell biology, U-87 MG is a human glioblastoma cell line that is commonly used in brain cancer research. [1] Formally known as U-87 MG (abbreviation for Uppsala 87 Malignant Glioma), the U87 cell line has an epithelial morphology and was obtained from a 44-year-old female patient in 1966 at Uppsala University.

Glioma cell lines, such as U87 glioblastoma cells, are cultured cells derived from human gliomas used extensively in cancer research to study tumor biology, genetics, and drug responses. They serve as models to understand tumor behavior and test therapeutic strategies.

Aug 31, 2016 · A cell line commonly used for research on gliomas is found to be different from the original tumor from which it was derived. The authors, whose laboratory developed the cell line almost 50 years ago, compared the genetics of this line …

Aug 31, 2016 · We find that the DNA profile of the widely used glioma cell line U87MG is different from that of the original cells and that it is likely to be a bona fide human glioblastoma cell line of unknown origin.

Problematic cell line: Misidentified. This cell line is not the original glioblastoma cell line established in 1968 at the University of Uppsala. As described in PubMed= 27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (Cellosaurus= CVCL_GP63) for the original U-87MG cell line.

Here, we aimed to unveil the proliferative and migrative capacity of GBM cell lines, U87 and LN229, and make a comparison with healthy astrocyte cell line, SVGp12.

U­87 is a glioblastoma, astrocytoma cell line derived from human malignant gliomas. The cells are adherent epithelial cells. The karyotype is hypodiploid female with a modal chromosome number of 44 in 48% of cells and a 5.9% rate of higher ploidy. There are several marker chromosomes.

IDH1 mutant-U-87 Isogenic Cell Line is a glioma IDH1R132H mutant isogenic line derived from the parental U-87MG (ATCC HTB-14) cell line. The IDH1R132H mutation is among the most common seen in glioma and serves as an important diagnostic marker in various stages of disease in patients.

Jan 29, 2010 · Here, we describe the broad genome sequencing of U87MG, a commonly used and thus well-studied glioblastoma cell line. One of the major features of the U87MG genome is the large number of chromosomal abnormalities, which can be typical of cancer cell lines and primary cancers.